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The hepatitis B virus (HBV) causes a potentially life-threatening liver infection called hepatitis B. It is a major global health issue. In some people, hepatitis B infection can become chronic, lasting more than six months. Infants and children are more likely to have chronic (long-term) hepatitis B infection. Even if the signs and symptoms are severe, most people with hepatitis B recover completely. Hepatitis B can be prevented using a vaccine that is both safe and effective. It is best to avoid hepatitis B infection because it can progress to chronic disease and liver cancer. If you've been infected, you can prevent the virus from spreading to others by taking certain precautions.