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It is a natural phenomenon that when air passes through a narrow passage, it creates a whistling sound. Similarly, when your airway is constricted or inflamed, it releases a high-pitched sound as air passes. This is known as wheezing. Wheezing is a sign of a medical condition related to your respiratory system. It can occur when you inhale or exhale air. Wheezing is common in chronic lung diseases, but it can also occur due to other reasons.