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Cystic Fibrosis is a chronic disorder of the exocrine glands, which is the most common genetic disease in whites. Exocrine glands are structures present throughout the body whose function is to produce and secrete vital secretions to help other organ systems to perform their physiological roles. Examples of such secretions are digestive juices, sweat, saliva, tears, milk, etc.
Cystic fibrosis involves multiple organ systems but mainly results in chronic respiratory infections, pancreatic enzymes insufficiency, and associated complications in untreated patients. End-stage lung disease is the leading cause of death. Most patients are diagnosed on newborn screening or at the age of 6-8 months; two-thirds of patients are diagnosed by one year of age.