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February 02, 2023 | Abigail Mckay

What does high CRP (C-Reactive Protein) indicate?

CRP is a protein that rises in response to inflammation. A high level of CRP in the blood is a sign of inflammation and may be caused by infections, injuries, autoimmune diseases, or cancer. If you have a high CRP, it's important to talk with your doctor to find out the cause, get treatment if needed, and reduce any associated risks.  C-Reactive Protein (CRP) is produced by the liver, and its concentrations double approximately every two hours during an infection or acute phase reaction. It’s generally accepted as a marker of systemic inflammation, but it can also be elevated due to tissue injury (including skeletal muscle injury from exercise) or other causes such as obesity, smoking, nephrotic syndrome from renal dysfunction, pregnancy, CHF, and some malignancies. Cancer cells produce large amounts of this protein, leading to tumor growth and metastases. Chronic low-level elevation of c-reactive protein (CRP), even within the “normal” range, has been associated with an increased risk for cardiovascular disease. This blog post will explore what high levels of CRP might indicate and why it’s important to talk with your doctor about any concerns.

CRP is a protein produced by the liver in response to inflammation

CRP, or C-reactive protein, is a biomarker produced by the liver that has been linked to signs of inflammation in the body. When our bodies experience an injury or infection, the liver responds by producing CRP, which can then be measured as an indicator of disease activity. Monitoring CRP levels for those with chronic inflammatory conditions can help pinpoint when treatment should be adjusted to reduce inflammation and related symptoms. Though it’s important to recognize that elevated CRP doesn’t necessarily mean a person is ill, it can be an important tool for identifying when intervention may help manage imbalances in health.

High CRP levels can indicate various conditions, such as infection, autoimmune disease, or cancer

C Reactive Protein (CRP) is a blood test that measures an individual's inflammation levels. Those with higher-than-normal CRP levels may be experiencing an underlying condition such as infection, autoimmune disease, or cancer. The American Academy of Family Physicians advises that anyone showing signs and symptoms of infection should get their CRP level tested to ensure a prompt and accurate diagnosis. It's important to rule out any potential health problems since early detection can improve health outcomes and quality of life for patients. That said, it's also important to note that high CRP levels can sometimes signify nothing and are not always linked to an underlying problem.

CRP levels can also be affected by lifestyle factors, such as diet and exercise

When considering the factors that affect C-Reactive Protein levels, it is important to keep in mind lifestyle choices such as diet and exercise. Eating a balanced diet with adequate fruit and vegetable intake can help manage CRP levels. Additionally, regular physical activity can be beneficial for reducing inflammation, which can contribute to higher CRP levels. While genetics certainly play a role in personal health, you can take ownership of your wellness by making positive lifestyle choices tailored to your needs.

What is the difference between CRP And Hs-CRP test?

C Reactive Protein (CRP) is a protein found in our blood that can be used to indicate the presence of inflammation. When it is at elevated levels, it can be an indicator of infection or disease. The main difference between CRP and High-Sensitivity C Reactive Protein (Hs-CRP) tests is the sensitivity each test offers regarding identifying inflammation. CRP tests measure larger amounts of this protein, so they will easily detect more sizable levels of inflammation, but Hs-CRP tests are far better at detecting small amounts of CRP. These smaller levels can become an important predictor for events like cardiovascular disease, even before symptoms become visible. Therefore, a Hs-CRP test can provide an earlier warning of potential problems, enabling medical professionals to offer proactive care when necessary.

There are many treatments available for conditions that cause high CRP levels

High levels of C Reactive Protein can cause a variety of uncomfortable and potentially serious health issues. Fortunately, there are many great treatments available that can help to reduce the levels of this protein if they become too elevated. These treatments include lifestyle changes such as healthier eating habits, exercise, or weight loss - depending on what works best for the individual - and medications like statins or anti-inflammatory drugs, which target and reduce specific proteins. With proper diagnosis and management of CRP levels, it is possible to reduce the risk of more serious conditions that could be exacerbated by having high CRP levels in the future.

If you have high CRP levels, you must talk to your doctor to find the cause. There are many treatments available for conditions that cause high CRP levels. You can also make lifestyle changes to lower your CRP levels. CRP test is available on Cura4U from Quest Diagnostics and Bio-Reference, with up to 80% discount with a home sampling facility. You can always talk to a Cura4U Physician to know if you need your CRP checked.



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Abigail Mckay

Abigail has been a nurse for five years, and throughout her time as a nurse, she has worked in multiple medical-surgical units as well as spent time in the infusion therapy clinic and endoscopy lab. She is passionate about preventative medicine through patient education regarding nutrition and exercise. Due to her passion, Abigail has gone on to earn two certifications including a certification in medical-surgical nursing (CMSRN) and a certification in holistic nursing (HNB-BC), in hopes of being able to better serve her patients. Abigail earned her Bachelor of Science in Nursing from Liberty University in Lynchburg, VA and now bettering patient education in the healthcare system through partnering with American TelePhysicians.