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Toothache, or pain in one or more teeth, is a common condition that occurs due to multiple causes. Most cases are directly associated with an injury, abnormality, or infection in the tooth or its supporting tissues. Your teeth are supported inside by an alveolar bone that forms sockets in which the tooth is aligned. Within these sockets, they are held in position by solid fibers called periodontal ligaments that attach the bone with the tooth’s outer surface. Finally, they are covered by a layer of soft tissue called gingiva or gums. Any irregularity within the tooth or its supportive structure can cause toothache. Some causes of a toothache may be of non-dental origin as well.