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Von Willebrand disease is a clotting disorder in which your blood lacks an essential protein called the Von Willebrand factor used for clotting blood. People with this disease either have a low level of Von Willebrand factor, or it does not function properly. This disease can cause a lifelong bleeding risk which can be debilitating for the affected person. There is no cure available for Von Willebrand’s disease, but some treatment measures and supportive care can improve life expectancy.