Vancomycin is an antibiotic. It is used in the treatment of serious infections caused by gram-positive bacteria. This test is used to measure the amount of Vancomycin present in the blood. Vancomycin was developed in the 1950s. It was originally prescribed when organisms proved to be resistant to penicillin or when the patient himself or herself was allergic to penicillin. The use of Vancomycin reduced with the introduction of other antimicrobials like methicillin but has seen an increase again with the arrival of new strains of staphylococcus, such as methicillin-resistant staphylococcus aureus, also known as MRSA. The levels of Vancomycin must be monitored during therapy in order to ensure effectiveness. The effectiveness of the drug is contingent on sustaining blood levels
that are a minimum concentration over the course of therapy. Higher levels of the drug must be avoided because high levels of Vancomycin can result in a severe side effect, particularly hearing damage, also known as ototoxicity, and kidney damage, also known as nephrotoxicity. The amount of Vancomycin given per dose is contingent upon various factors. These include things like kidney function, as well as the age and weight of the person, in addition to any nephrotoxic drugs the patient may be on. Decreasing kidney function may impact the clearance of Vancomycin from a patient’s body. It may lead to a higher concentration of the antibiotic in the blood. If the person is given a small amount of the drug and is not able to sustain an efficient minimum amount of it in the blood, then it is not likely that the treatment will prove to be effective. The test can also be used to ensure that the amount of drug in the blood remains at a concentration that is effective therapeutic; insofar, it is effective but not so excessive that it causes damage. Vancomycin is administered intravenously to treat infections like endocarditis, septicemia, infection of the bone, meningitis, and pneumonia. The drug is most commonly used to treat methicillin-resistant staphylococcus epidermidis and methicillin-resistant staphylococcus aureus infections. Especially when they are linked with implanted prosthetic devices like heart valves and artificial hips and catheters, it may also be administered to people before specific surgeries and dental procedures in order to prevent the development of an infection. Vancomycin must be administered intravenously in order to get the drug into circulation because orally administered Vancomycin is poorly absorbed by the digestive tract. However, oral vancomycin medicine is administered to treat infections in the digestive tract where it is not necessary for the drug to be absorbed into the blood.