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Anti-Mullerian Hormone AMH-Male

Also Known as:    AMH hormone test, müllerian-inhibiting hormone, MIH, müllerian inhibiting factor, MIF, müllerian-inhibiting substance, MIS

What is an Anti-Mullerian Hormone (AMH ) test?

The anti-müllerian hormone (AMH) level in the blood is measured in this test. Both males and females produce AMH in their reproductive tissues. Your age and gender determine the role of AMH and whether or not your levels are normal.

 AMH plays an integral part in developing a baby's sex organs while still in the womb. A baby's reproductive organs begin to develop during the first weeks of pregnancy. The baby will be born with the genes to be either a male (XY genes) or a female (XX genes). If the baby possesses a male (XY) gene, high levels of AMH and other male hormones are produced. This inhibits the development of female organs while encouraging the growth of male organs. Organs of both sexes may form if there isn't enough AMH to impede the development of female organs. When this happens, a baby's genitals may be challenging to distinguish between male and female. The term for this is ambiguous genitalia (Intersex). 

What is the test used for?

AMH tests can be used for a variety of purposes, including:

  • Predict the onset of menopause, the period in a woman's life when her monthly periods have stopped, and she can no longer become pregnant. It usually begins when a woman reaches the age of 50.
  • I am finding out the cause of early menopause.  
  • Assist in determining the cause of amenorrhea or menstrual irregularities.  It's more common among girls who haven't started menstruation by 15 and women who have missed multiple menstrual cycles.
  • Aid in diagnosing polycystic ovarian syndrome (PCOS), a hormonal condition that becomes a prevalent cause of female infertility.
  • Coupled with chromosome testing, hormone testing, and sometimes imaging scans may be ordered to help determine the sex of an infant with external genitals that are not male or female (ambiguous genitalia).
  • They are used as a tumor marker to monitor treatment effectiveness for women with certain types of ovarian cancer and check for recurrence.

Why and when do you need this test?

In the fetus, AMH is essential for sexual differentiation. A developing fetus might develop either male or female reproductive organs during the first few weeks of pregnancy. The two testicles in a baby boy produce AMH and androgens, which inhibit the development of female reproductive organs (the Müllerian ducts seen in both male and female fetuses) while promoting the production of other male reproductive organs. Both male and essential female organs may develop if a sufficient amount of AMH is not present during this process.

If the testicles haven't descended but are still in the abdomen, this test can be used to see if they're working correctly by evaluating the AMH level.

What kind of sample is required for the test?

A small needle will be used by a healthcare professional to obtain a blood sample from a vein in your arm.  A small amount of blood will be collected into a test tube or vial once the needle is inserted. When the hand goes in or out, it may sting a little. It usually takes less than five minutes to complete this process. 

Do you need to prepare for the test?

An AMH test does not require any specific preparation. 

Are there any risks to this test?

Having a blood test carries relatively little risk. You may experience minor pain or bruising where the needle gets inserted, but most symptoms disappear quickly.

What do the test results mean?

A low level of AMH in a male child could indicate a hereditary or hormonal issue, resulting in genitals that are not identified as male or female. If the baby's AMH levels are normal, they may have working testicles but not in the appropriate place. Surgery or hormonal therapy can be used to treat this condition.

It is always recommended to consult your healthcare provider if you have any questions regarding your test results. 

Related Tests: Follicle-stimulating Hormone (FSH), Luteinizing Hormone (LH), Estrogens, Testosterone free, Progesterone

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