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Acute kidney failure (AKF), also known as acute kidney injury (AKI), is a rapid decline in renal function manifested by a rise in serum creatinine or a reduction in urine output, or both, within seven days.
Kidneys are paired structures located near the back wall of your abdomen and side areas called flank, one on each side of the spine whose function is to filter the waste materials out of the blood and produce urine as a by-product. Once your kidneys reduce their filtering abilities, harmful levels of debris can build up, and the chemical makeup of your blood can become unbalanced. Those who have had AKI have a higher risk of having chronic renal disease later in life.
Acute renal failure is more prevalent among people who have already been admitted to a hospital, especially those who are seriously ill and require critical care. It is managed by the treatment of the root cause as well as a supportive therapy, such as renal replacement therapy.